TRANSCRIPTION FACTOR CLUSTERS REGULATE GENES IN EUKARYOTIC CELLS

Transcription factor clusters regulate genes in eukaryotic cells

Transcription is regulated through binding factors to gene promoters to activate or repress expression, however, the mechanisms by which factors find targets remain unclear.Using single-molecule fluorescence microscopy, we determined in vivo stoichiometry and spatiotemporal dynamics of a GFP tagged repressor, Mig1, from a paradigm signaling pathway

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Practice patterns among early-career primary care (ECPC) physicians and workforce planning implications: protocol for a mixed methods study

Introduction Canadians report persistent problems accessing primary care despite an increasing per-capita supply of primary care physicians (PCPs).There is speculation that PCPs, especially those early in their careers, may now be working less and/or choosing to practice in focused Quilt Set clinical areas rather than comprehensive family medicine,

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A Specific Resistance Gene to Leptosphaeria maculans, Rlm11, Has a Limited Impact on Brassica napus Mycobiota Compared with Plant Compartment or Cropping Season Effects

One important ecological Lego Boxed question regarding the use of plant resistance genes against fungal pathogens concerns whether and how such resistance genes may modify pathogenic or beneficial members of the plant-associated microbiota.We studied the impact of a plant resistance gene by analyzing the mycobiota associated with Brassica napus org

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